Abstract
Abstract
Background Skin grafting is a closure technique used in dermatology most commonly to close wounds created by the removal of skin damaged. Although currently less favored than flap closures, grafting can produce a good cosmetic result.
Aim of study: The aim of the present study was to investigate the grafting of the skin of albino male rabbits by N-acetyl cysteine (NAC) and Serratiopeptidase, then compare between their effect on the skin grafting of rabbits.
Methodology: 9 rabbits were divided into three groups each group have 3 animals as following Group 1 (G1) as a control (skin grafting without any drug), skin was taken from shoulder to femoral area. Group 2 (G2) the skin graft was taken from the same area in the G1 with using Serratiopeptidase, while the group 3 (G3) the skin graft was taken from the same area in G1 with using NAC.
Results: The results have been shown that both of the NAC and Serratiopeptidase good enhancement effects on the skin graft, and showed better enhancement effects on the hematology, histology and AST parameters.
Conclusion: results were show both of NAC and serratopeptidase can be used to enhance the skin graft will cause increase in the hematology, histology and AST levels .