الملخص

Oyster mushroom (Pleurotus ostreatus) contains bioactive components such as polysaccharides, beta-glucans and phenolic compounds; it is gaining popularity as a natural alternative to antimicrobial growth promoters in poultry production. These substances possess antioxidant, antimicrobial, and immunomodulatory properties that may improve the health and productivity of broiler chickens. The purpose of this study was to assess how supplementing with Pleurotus ostreatus affected liver function, antioxidant status, lipid profile, and biochemical markers. Under usual settings, two groups of broiler chickens were randomly assigned: a treatment group that received 2% Pleurotus ostreatus supplementation for six weeks, and a control group that received a basal diet. Blood samples were taken for serum analysis at the conclusion of the experiment. An independent t-test with a statistical significance level of P < 0.05 was used to analyze the data, which are presented as mean ± standard deviation. Compared to the control and treatment groups, the treatment group showed lower levels of glucose, cholesterol, triglycerides, very low-density lipoprotein (VLDL), alanine aminotransferase (ALT), and aspartate aminotransferase (AST). A significant decrease in triglycerides, VLDL, and AST was observed. While glutathione peroxidase (GSH-Px) levels decreased only slightly, albumin, globulin, and catalase levels increased slightly. These results suggest that oyster mushroom (Pleurotus ostreatus) may improve liver function and lipid metabolism in broiler chickens.